Inspired by, that is, stolen from, The AV Club: http://www.avclub.com/article/what-movie-tv-or-book-moment-will-always-make-you--223485?utm_medium=RSS&utm_campaign=feeds
For me it's the bit in Scrooged where Frank Cross gets picked up by a demented taxi driver, who turns out to be The Ghost of Christmas Past.
He says, "I know everything about you Frankie. You see," and he turns around, "I'm the ghost."
Gets me every. Time.