A couple of nominees from me
One so quintessentially DiS, it has to my favourite: Can We Have One Of Those Threads Where We ^This The Wetherspoons We've Been In Please? http://drownedinsound.com/community/boards/social/4438939
Describe Your Sex Life In Four Pokémon Moves... http://drownedinsound.com/community/boards/social/4285336
Most read will be revealed in first week of the year, but I can tell you that Malcolm Tucker quotes is in the top 100!
...any guesses what else might make the top 20 most read?
STATS: Jan 1st - Dec 12th
Unique Visitors 3,367,605
(Although we have 5 days of data missing when the site relaunched)
Here's what were the most read at the half-way mark http://drownedinsound.com/community/boards/social/4429484