The novel is a detective story set in an alternative history version of the present day, based on the premise that during World War II, a temporary settlement for Jewish refugees was established in Sitka, Alaska, in 1941, and that the fledgling State of Israel was destroyed in 1948. The novel is set in Sitka, which it depicts as a large, Yiddish-speaking metropolis.
As of December 2008, a film adaptation is in pre-production, to be written and directed by the Coen brothers.
I've not read a word of his so quite looking forward to it. Sounds like a pretty interesting premise.