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Terry Pratchett has Alzheimer's
http://news.bbc.co.uk/2/hi/uk_news/7141458.stm
Never been much of a Discworld fan, but I really liked the first few and love Good Omens, so this is quite sad. In fact, its actually quite sad for reasons very different to my reading preferences. Hopefully when it sets in it won't be too painful for him, his friends and his family.