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What divides this for you?
Tottenham Court Road for me, then its extension into the A400.
so it is things that aren't central. so there is no divide. other than the whole of central london.
but I still split the center into an east and a west, although obviously I wouldn't refer to Holborn / St Pauls as East London
by one developer to brand holborn as "midtown" a few years ago. there was a big sign on a development with "MIDTOWN'S HOTTEST NEW ADDRESS" on the side in huge letters, it used to make me giggle.
That actually freaks THE FUCK out of me...
the east side of gray's inn road has an EC1 postcode, while the west side is WC1.
that's all you can go with, surely?