I saw this about a month ago and ever since, I've been trying to work something out...
...Timothy's Dalton's character at one point says "This really hurts", and I KNEW immediately that I'd heard that line before delievered in the exact same manner. But where? I thought it might have been Shaun Of The Dead or Spaced, but it didn't seem right, to me.
The answer hit me last night: Garth Marenghi's Darkplace. First episode, the bit where the guy blows up and all that's left is his head.