By about a country mile for me. 10 years of forward thinking/righteous/phat/whuteva hip hop beats, over 200 tracks, 80 minutes long, all impeccably mixed; DJ Premier through Hudson Mohawke, really amazing stuff. Probably the only thing I've been able to play to everybody I know with unanimously positive reactions.
Wireblock mix for xlr8r
Really masterful, takes in everything from the usual glaswegian hip hop stuff to lost 80s house classics, UK Funky, Bristol dubstep, and err Ying Yang Twins. Club music done perfectly, rules so hard. See also: Jackmaster's retrospective mix for Dress 2 Sweat.
Hotflush Podcast 03: Scuba
Hotflush label boss puts in an amazing mix demonstrating the cross pollination that comes as a result of being a UK dubstep/2 step dude with a residency at Berghain. Amazing exploratory, deep n dark Techno/Dubstep/Garage/2 Step with a few older classics and a surprise appearance from.. Tom Vek?? Also great is his mix for http://mnmlssgs.blogspot.com which should is available on the same page. Scuba was hands down the best DJ I saw all year and probably all of my life!
As well as these, countless Joy Orbison, Untold and Jackmaster mixes, Bok Bok's sub fm radio shows, Dusk & Blackdown's rinse shows, Martyn's forthcoming Fabric mix and much much much more.
Any other suggestions?