A blood brother is a male who swears loyalty to another male.

Blood Brothers may also refer to:

• Blood Brothers (1973 film), a Hong Kong film directed by Chang Cheh
• Blood Brothers (2007 film), a Chinese film directed by Alexi Tan
• Blood Brothers (short film), a 2007 AIDS-awareness film produced by the Bill Gates foundation
• Jiang Hu (film) (Blood Brothers), a 2004 Hong Kong gang film
• Blood Brothers (1993 film), a made-for-television film featuring Richard Yearwood
• Bloodbrothers (film), a 1978 film, based on a novel by Richard Price, starring Tony Lo Bianco
• The Blood Brothers, the working title of the 2007 Chinese film The Warlords

• Blood Brothers (1965 novel), a novel by John McIntosh
• Blood Brothers (comics), two Marvel Comics characters
• Bloodbrothers (novel), a novel by Richard Price
• Blood Brother (novel), a novel by Elliott Arnold
• Blood Brother (Traces novel), a novel by Malcolm Rose

• Blood Brothers (musical), a musical by Willy Russell
  • Blood Brothers (musical album), a 1995 London cast recording of the musical
• The Blood Brothers (band), an American post-hardcore band
• Blood Brothers (documentary), a documentary about a Bruce Springsteen & the E Street Band reunion
• Blood Brothers (EP), an EP by Bruce Springsteen & the E Street Band released with the documentary
• Blood Brothers (album), an album by Outerspace
• Blood Brothers (Kastro and E.D.I. album)
• Bloodbrothers, an album by The Dictators
• "Blood Brothers", a song by Iron Maiden from Brave New World
• "Blood Brothers", a song by Malevolent Creation from Eternal
• "Blood Brothers", a song by Manowar from Gods of War
• "Blood Brothers", a song by Papa Roach from Infest

• "Blood Brothers" (CSI: Miami), an episode of CSI: Miami
• "Blood Brothers" (M*A*S*H), an episode of M*A*S*H
• "Blood Brothers" (The Outer Limits), an episode of the 1990s version of The Outer Limits
• "Blood Brother" (Roswell), an episode of Roswell
• "Blood Brothers", an episode of MacGyver
• "Blood Brothers: The Joey DiPaolo Story", an episode of Lifestories: Families in Crisis about Joey DiPaolo, an 11-year-old living with HIV

• Blood Brothers (World of Darkness), a vampire bloodline in the role-playing game Vampire: The Masquerade
• Blood Brothers Machine Company, an American company